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Dr. Chiou-Hwa Yuh


Dr. Chiou-Hwa Yuh

Institute of Molecular and Genomic Medicine, ROC

Biography

Chiou-Hwa Yuh has completed her PhD from National Yang-Ming University in Taiwan, and Postdoctoral studies from California Institute of Technology in USA. She was famous in Developmental Gene Regulatory Networks. She initiated the systematic analysis of hepatocellular carcinoma (HCC) in mouse model, and established transgenic zebrafish model. She further developed the drug screening platform to identified novel small molecules which are effective in treatment HCC and lower toxicity compared to Sorafenib. She has published 41 papers in reputed journals and has been serving as an editorial board member of repute journals.

Abstract

Abstract : Distinct roles of α-1,2-mannosidase subtypes in hepatocarcinogenesis: MAN1A1 is an oncogene and MAN1C1 is a tumor suppressor gene